What antihypertensives are contraindicated in pregnancy?

Why are ACEI and ARBs contraindicated in pregnancy?

It is well accepted that angiotensin-converting enzyme (ACE) inhibitors are contraindicated during the second and third trimesters of pregnancy because of increased risk of fetal renal damage. First-trimester use, however, has not been linked to adverse fetal outcomes.

Which antihypertensives are contraindicated?

Potassium-sparing diuretics are contraindicated in patients with chronic kidney disease, hyperkalemia, and caution is necessary when combining them with ACE inhibitors, ARBs, and aliskiren. [46] They are contraindicated in patients with hypersensitivity to this class.

Why is amlodipine contraindicated in pregnancy?

Amlodipine and Pregnancy

There are no good studies in pregnant women. Amlodipine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known if amlodipine will harm your unborn baby.

What antihypertensive drug is safe for pregnancy?

The choice of antihypertensive drugs also is discussed; methyldopa, labetalol, and nifedipine, among others, appear safe for use in pregnancy, whereas angiotensin converting enzyme inhibitors and angiotensin receptor blockers should be avoided.

Are ACE inhibitors teratogenic?

Specifically, these drugs were associated with increased infant risks for cardiovascular and nervous system anomalies. ACE inhibitors, long known to be teratogenic when used in the last two trimesters of pregnancy, have been considered safe in the first trimester.

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What are the 7 classes of antihypertensive medications?

The classes of blood pressure medications include:

  • Diuretics.
  • Beta-blockers.
  • ACE inhibitors.
  • Angiotensin II receptor blockers.
  • Calcium channel blockers.
  • Alpha blockers.
  • Alpha-2 Receptor Agonists.
  • Combined alpha and beta-blockers.

Is metoprolol contraindicated in pregnancy?

Are there any risks of taking metoprolol in pregnancy? A small number of pregnant women specifically taking metoprolol have been studied, with no concerns raised that its use causes birth defects or preterm birth. Metoprolol belongs to a family of medicines called beta blockers.

Can I take Norvasc while pregnant?

Norvasc and Pregnancy

Norvasc falls into category C. There are no good studies in pregnant women. Norvasc should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known if Norvasc will harm your unborn baby.

Is chlorthalidone safe during pregnancy?

Taking chlorthalidone during pregnancy may cause side effects in the newborn baby, such as jaundice (yellowing of the skin or eyes), bruising or bleeding, low blood sugar, or an electrolyte imbalance. Do not start or stop taking chlorthalidone during pregnancy without your doctor’s advice.

What are ACE inhibitors examples?

Angiotensin-converting enzyme inhibitor (ACE inhibitors) drugs include Benazepril (Lotensin), Captopril (Capoten), Enalapril/Enalaprilat (Vasotec oral and injectable), Fosinopril (Monopril), Lisinopril (Zestril and Prinivil), Moexipril (Univasc), Perindopril (Aceon), Quinapril (Accupril), Ramipril (Altace), and …